Dicantharidylethylene-diamin-mono-aurocyanid and process of making same.



[ UNITED STATES PAEENT OFFICE.

GUSTAV SPIESS AND ADOLF FELDT, OF FRANKFORT-ON-THE-MAIN, GERMANY, ASSIGN- ORS'TO FARBWERKE V'OR-M. MEISTER LUCIUS & BRfi'NING, OF H6CHST-ON-THE- MAIN, GERMANY, A CORPORATION OF GERMANY.

DICANTHARIDYLETEFYLENE-DIAMIN-MONO-AUROCYANIQ; AND PROCESS 'OF MAKING SAME.

1,115,5il9. Specification of Letters Patent.

No Drawing.

To all eehom it may concern Be it known that we, GUSTAV SPrEss, Ph. D., professor of medicine, and ADoLF FELn'r. Ph. D., doctor of medicine, citizens of the Empires of Germany and'Russia, re-

microorganisms in the human and animal body. Now we have found that the best way of rendering the said aurocyanid less poisonous to animal and human organisms,

without losing thereby its specific action upon microorganisms, is to form di-cantharidylethylene diamin-monoaurocyamd. This compound is obtained by causing an aqueous or alcoholic solution of. cantharidylethylenediamin to act upon aurocyanid. The new body has most probably the formula:

It is a light-yellow, crystalline product, readily dissolving in water with a slightly alkaline reaction.

The procedure for producing the new compound may, for instance, be as follows: 10

grams of cantharidylethylenediamin are dissolved in 50 cc. of absolute alcohol and heat I ed with 5 grams of aurous cyanid m a closed-up tube to 100 C. for 6-8 hours while shaking. The small quantity of gold Patented Nov. 3, 1914.

Application. filed January 16, 1914. Serial No. 812,576.

which separates is filtered off, the filtrate is evaporated in vac-a0 and the residue ex tracted with acetic ester. The undissolved portion. is filtered ofii, washed with acetic ester and the substance thus obtained is recrystallized in a small quantity of absolute alcohol.

The cantharidylethylenediamin-mono-aurocyanid forms a yellowish, crystalline powder; it melts at l48 150 C.; it readily dissolves in water with a slightly alkaline reaction; when heated it decomposes, leaving metallic gold.

Having now described our invention, what we claim is:

1.- The process of preparing di-cantharidylethylene-diamin-mono-aurocyanid, which consists in causing asolution of cantharidyl-ethylenediamin to act upon aurocyanid (AuCNL 2. As a newproduct, the di-cantharidylethylene diamin mono aurocyanid, having most probably the formula:

forming a yellowish crystalline powder, melting at 1428 150 C., easily dissolving in water with a slightly alkaline reaction, and decomposing, when heated, leaving then metallic gold.

It testimony whereof, we aflix our signa tures in presence of two witnesses.

GUSTAV SPIESS. ADOLF FELDT.

Witnesses J EAN GRUND, ,CARL GRUND. 

